Modafinil Medical Advice

 

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Modafinil Enhances Cognitive Performance

Research conducted by, Paul Gerrard1 and Robert Malcolm2. I have summarise this article for easy reading.

Outline

In this review  Paul Gerrard1 and Robert Malcolm2 summarize and discuss published research on modafinil’s neural, cytoprotective, and cognitive effects.Also suggested is the neurocognitive mechanisms responsible for modafinil’s cognitive enhancing effects.

Modafinil primary use is for the treatment of sleep disorders & clinical trials are under way for it’s use in stimulate addiction.

Previous studies have shown that modafinil has antioxidative and neuroprotective effects.

Introduction

Modafinil works that we know. How it works exactly that we don’t.

In 1998 modafinil was approved by the Food and Drug Administration for the treatment of narcolepsy.

A decade later there is evidence showing that it is effective for treating several sleep disorders

There are ongoing clinical trials for its use in;

fatigue

cocaine addiction

attention deficit disorder

depression

seasonal affective disorder

bipolar depression

nicotine addiction

and schizophrenia

Preclinical evidence indicates possible use in the treatment of neurodegenerative diseases.

Discussion on Modafinil Effects

It is clear that modafinil has noteworthy neuroprotective effects as well that involve some sort of antioxidative process.

While these effects may be coincidental to modafinil’s wake-promoting effects, the role of the ATP breakdown product adenosine in homeostatic sleep regulation is at least suggestive that modafinil’s neuroprotective effects are not irrelevant to the consideration of modafinil’s wake-promoting effects.

It a possibility that modafinil could directly act on enzymes in the brain’s free-radical scavenging system

(eg, glutathione peroxidase or superoxide dismutase) to directly reduce free-radical levels.

Because, reactive oxygen species feed back positively on the mitochondrion to reduce ATP production and possibly enhance free radical production.

Conclusion of some recent studies

A number of studies testing modafinil’s effects on neurocognitive functioning tend to confirm that

modafinil enhances cognitive performance in healthy volunteers, especially with regards to executive function.

Research showed that modafinil did improve neurocognitive performance.

Summary

The bulk of research into modafinil’s wake-promoting mechanism has focused mostly on possible extracellular activities of modafinil.

Paul Gerrard1 and Robert Malcolm2 propose that more work be done on examining potential intracellular mechanisms of modafinil and finding a point of convergence of modafinil’s stimulant and neuroprotective effects.

It is likely that modafinil both enhances cellular metabolism and reduces free-radicals in neurons

Reduction in brain oxidation or an increase in cortical creatine could promote vigilance

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Medical Usages

Armodafinil is FDA-approved and available by prescription only in a lot of countries.

However we deliver to most countries and have had no problems to date.

Please note we do not send order over 300 together in 1 packet. Orders 300 and over are broken down in 200 tablet lots and shipped apart.

Safety Measures
Although armodafinil is a wonder supplement, caution is advised for use on patients suffering from any underlying heart conditions and hypertension.

If an individual is suffering from conditions such as angina, myocardial infarction, hypertension, hypertension in pregnancy, or mitral valve disorders, it is completely inadvisable to take the drug.

It should not also be taken during pregnancy and while breast feeding. Armodafinil should not be taken with chocolates, alcohol, and opioid s like oxycodone, codone, and fentanyl.

Medication Interactions
Before receiving your Armodafinil prescription from your doctor, let him/her know about the medications you currently take – including prescription and non-prescription medications, supplements, and vitamins.

You must inform your doctor if you take medications such as:

Those that increase the enzymatic activity of CYP3A4. These medications include nimodipine (Nimotop), rifampin (Rifadin), carbamazepine (Carbatrol, Equetro, Tegretol), phenytoin (Dilantin), St John’s Wort, and phenobarbital.

Those that make use of the enzyme CYP2C19 such as phenytoin (Dilantin), omeprazole (Prilosec), propranolol (Inderal), and diazepam (Valium).

Those that are used for hormonal birth control processes such as birth control pills, patches, implants, shots, vaginal rings, and IUDs. Those that block proteins like CYPA4 in the body.

These medications include antifungals (such as posaconazole, ketoconazole, voriconazole, and itraconazole), and macrolide antibiotics such as erythromycin, telithromycin, and clarithromycin.

Warfarin
There are still other medications that interact with Armodafinil Online, as such, it would be ideal to ask your healthcare professional for information and guide on the best procedure for your situation.

Food Interactions
Some medications interact with certain foods. Your doctor may advise you to avoid eating some foods during the course of the medication.

Although Armodafinil Online does not interact with specific foods, it would be ideal to discuss with your doctor about eating and drinking grapefruit and grapefruit juice respectively.

However, taking Armodafinil Online does not generally affect your diet pattern.

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Health Precautions

If you have any medical conditions, you would do well to let your doctor know before taking Armodafinil Online

It is especially important to tell your doctor about the following conditions:

Allergy to Armodafinil Online or any of its constituents

Mental illness history

Kidney or liver problems

Heart attack or heart related problems

High blood pressure

History of addiction or abuse of alcohol or drug

Pregnancy or planning for pregnancy. It is not very clear whether taking Armodafinil Online could harm your unborn child.

Breastfeeding. It is not clear whether taking Armodafinil Onlinecan affect the quality of your milk

Armodafinil was design to deal with extreme daytime drowsiness connected with obstructive sleep apnea, narcolepsy, and shift work condition.

Armodfinil is now utilized a lot off-label to deal with it attention deficit disorder, persistent, tiredness and significant depressive condition.

Storage and Regulations
It is recommended that you store Armodafinil at temperature range of 20° to 25°C (or 68° to 77°F).

Remember to keep Armodafinil, and of course all medications out of the reach of children.

Since Armodafinil Online can lead to dependence or may even be abused, it is federally controlled.

Along with only taking it according to your doctor’s prescription, it would also be ideal to store it in a safe place so it is not misused.


“Pass any standard workplace drug test with Modafinil”