An in-depth comparison
Author: Shane Southgate @Dafinil.com
- Who’s the winner? An in-depth comparison between the two supplements
- An overview
- A basic comparison
- Difference in the components
- How are the mechanism of action different?
- Which is better?
- The final thoughts
Through this article, we’re not promoting the two supplements; we’re just helping you choose the best one basis your requirement.
Nowadays, they are also being used to improve athletic performance as well as cognitive performance.
In the upcoming sections, we’ll discuss both the supplements in detail and draw a fair comparison between the two to help you make an informed decision.
Since they follow different chemical mechanisms and have different chemical structure, their possible side effects and clinical forms are different.
While Adderall is mainly prescribed for narcolepsy and ADHD, Modafinil is recommended for obstructive sleep breathing cessation, excessive sleep during the daytime because of narcolepsy, and sleep disorders related to shift-based jobs.
In some cases, Modafinil is also prescribed to relieve the fatigue and exhaustion caused by cancer and depression.
Modafinil is classified as a schedule IV drug due to its lower possibility for abuse.
On the other hand, Adderall is classified as a schedule II drug due to its increased potential for drug abuse and psychological and physical addiction.
The following amphetamine salts come together to form Adderall:
• D-amphetamine sulfate
• L-amphetamine aspartate
• D-amphetamine (d-amphetamine) saccharate
• L – amphetamine (l-amphetamine) sulfate
Modafinil is an amalgamation of the two structural modifications of 2- [(diphenyl methyl)sulfinyl]acetamide.
The two variants of the molecule are mirror images and have varying properties.
Adderall functions by stimulating the release of neurotransmitters such as adrenaline, dopamine, and norepinephrine.
Moreover, Adderall also works to protect neurotransmitters against being stored in the nerve cell, broken down, or utilized.
To make this possible, Adderall block the proteins that pull the neurotransmitters inside the cells.
Another important action point of Adderall is the protection of dopamine.
Adderall stops dopamine from getting deposited inside the cell compartments so that enough dopamine is available in the brain to enhance the perceived intelligence.
Lastly, Adderall triggers the alpha- and beta-adrenaline receptor areas.
On stimulation, the beta-adrenaline receptor stimulates the brain by improving the heart rate, enhancing blood circulation to the muscles, and flow of blood from the heart.
Modafinil plays a critical role in blocking the dopamine transport.
This leads to more availability of dopamine in the brain. Modafinil is also responsible for spiking the dopamine levels in the brain.
Increase dopamine levels are responsible for keeping you awake, helping you think creatively, boosting your confidence, and keeping you active throughout the day.
Based on all the comparison points mentioned above, we have a clear winner. Any guesses?
Well, the winner is Modafinil.
Here are two reasons why:
Based on a study where an army personnel was made to stay awake for almost 64 hours for completing their tasks and tested on mood and cognition, it was found that the effect of Adderall and Modafinil was similar in retaining the reasoning abilities and temperament.
So, Modafinil is safer and does not lead to any kind of drug abuse or addiction.
The final thoughts
Adderall is considered to be unsafe due to its addiction potential and therefore not recommended for medical use.
So, if you want to choose between the two supplements, we recommend you go for Modafinil.
However, you must ensure that you’re consuming the drug in the prescribed quantity as an overdose of the drug can be life-threatening.